New PDF release: A Hole in the Head: More Tales in the History of

By Charles G. Gross

Neuroscientist Charles Gross has been attracted to the historical past of his box when you consider that his days as an undergraduate. A gap within the Head is the second one choice of essays within which he illuminates the learn of the mind with attention-grabbing episodes from the previous. This volume's stories variety from the historical past of trepanation (drilling a gap within the cranium) to neurosurgery as painted by way of Hieronymus Bosch to the invention that bats navigate utilizing echolocation.

The emphasis is on blind alleys and blunders in addition to triumphs and discoveries, with old practices attached to fresh advancements and controversies. Gross first reaches again into the beginnings of neuroscience, then takes up the interplay of paintings and neuroscience, exploring, between different issues, Rembrandt's "Anatomy Lesson" work, and at last, examines discoveries through scientists whose paintings used to be scorned of their personal time yet confirmed right in later eras.

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By Charles G. Gross

Neuroscientist Charles Gross has been attracted to the historical past of his box when you consider that his days as an undergraduate. A gap within the Head is the second one choice of essays within which he illuminates the learn of the mind with attention-grabbing episodes from the previous. This volume's stories variety from the historical past of trepanation (drilling a gap within the cranium) to neurosurgery as painted by way of Hieronymus Bosch to the invention that bats navigate utilizing echolocation.

The emphasis is on blind alleys and blunders in addition to triumphs and discoveries, with old practices attached to fresh advancements and controversies. Gross first reaches again into the beginnings of neuroscience, then takes up the interplay of paintings and neuroscience, exploring, between different issues, Rembrandt's "Anatomy Lesson" work, and at last, examines discoveries through scientists whose paintings used to be scorned of their personal time yet confirmed right in later eras.

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2004) Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathology, 14, 164–174. , Dornmair, K. et al. (2004) Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid. Proceedings of the National Academy of Sciences of the United States of America, 101 (8), 2428–33. M. & Dragunow, M. (2014) The human side of microglia. Trends in Neurosciences, 37 (3), 125–135.

2008). Most profound evidence for oxidative injury has been found in oligodendrocytes and myelin, as well as in axons and degenerating neurons. , 2013). , 2012). Inflammation in Stroke Lesions The primary cause of tissue injury in stroke lesions is hypoxia and ischemia. , 2009). This assumption is mainly based on evidence from experimental models, in which various different anti-inflammatory treatment strategies have been shown to reduce clinical deficit and lesion size. , 2013). Several potential explanations have been forwarded for this unsatisfactory situation.

H. (1997) Axonal damage in acute multiple sclerosis lesions. Brain, 120, 393–399. , Lim, J. et al. (2012) NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury. Brain, 135, 886–899. , Höftberger, R. et al. (2013) Disease-specific molecular events in cortical multiple sclerosis lesions. Brain, 136, 1799–1815. , Ritter, T. et al. (2001) Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis.

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A Hole in the Head: More Tales in the History of Neuroscience by Charles G. Gross


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