By American Academy of Ophthalmology, James C. Bobrow MD
Stories the anatomy, body structure, embryology and pathology of the lens. Covers the epidemiology, overview and administration of cataracts and offers an outline of lens and cataract surgical procedure, together with targeted occasions. part eleven additionally walks the reader via making a suitable differential analysis and designing a administration plan for intraoperative and postoperative issues of cataract surgery.
Upon finishing touch of part eleven, readers can be capable to:
Identify congenital anomalies of the lens
List kinds of congenital and purchased cataracts
Describe the organization of cataracts with getting older, trauma, drugs, and systemic and ocular diseases
Describe the assessment and administration of sufferers with cataract and different lens abnormalities
Read or Download 2014-2015 Basic and Clinical Science Course (BCSC): Section 11: Lens and Cataract PDF
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Extra info for 2014-2015 Basic and Clinical Science Course (BCSC): Section 11: Lens and Cataract
Histologically, the nucleus in nuclear cataract is difficult to distinguish from the nucleus of normal, aged lenses. Investigations by electron microscopy have identified an increased number oflamellar membrane whorls in some nuclear cataracts. The degree to which protein aggregates or these membrane modifications contribute to the increased light scattering of nuclear cataracts is unclear. CHAPTER 4: A Pathology • 41 8 nucleus Subcapsular vacuoles Figure 4-2 Nuclear cataract viewed with diffuse illumination (Al and with a slit beam (BJ.
C, Schematic of nuclear cataract. , division of CIBA-GEIGY Corp. Modified with permission from Clinical Symposia , Illustration by John A. ) Cortical Cataracts In contrast to nuclear cataracts, cortical cataracts are associated with the local disruption of the structure of mature lens fiber cells. Once membrane integrity is compromised, essential metabolites are lost from the affected cells. This loss leads to extensive protein oxidation and precipitation. Cortical cataracts are usually bilateral but are often asymmetric.
Wedge-shaped opacities (often called cortical spokes or cuneiform opacities) form near the periphery of the lens, with the pointed end of the opacities oriented toward the center (Fig 4-4). Since these peripheral opacities occur in fiber cells that extend from the posterior to the anterior sutures, they affect only the equatorial regions of the fiber cells. In the initial stages of the cataract, affected fiber cells remain clear at their anterior and posterior ends. The cortical spokes appear as white opacities when viewed with the slit-lamp biomicroscope and as dark shadows when viewed on retroillumination.
2014-2015 Basic and Clinical Science Course (BCSC): Section 11: Lens and Cataract by American Academy of Ophthalmology, James C. Bobrow MD